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Pioglitazone uses: This medication is a combination of 2 drugs, pioglitazone and glimepiride. It is used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). Effectively controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, circulation problems, and sexual function problems (impotence).Pioglitazone belongs to a class of drugs known as thiazolidinediones or "glitazones." It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar.Glimepiride belongs to a class of drugs known as sulfonylureas. It works by causing the release of your body's natural insulin.How to use Pioglitazone/Glimepride OralRead the Patient Information Leaflet provided by your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.Take this medication by mouth, usually once daily with the first main meal of the day or as directed by your doctor.The dosage is based on your medical condition and response to treatment. Do not take more than 45 milligrams of pioglitazone a day.Use this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. Monitor your blood sugar levels on a regular basis, and share the results with your doctor.It may take up to 2 to 3 months before you get the full benefit of this drug.When switching from individual diabetes drugs to this combination product, your doctor may ask you to check your blood sugar more often to make sure you do not have a sudden attack of low blood sugar (hypoglycemic reaction) when starting this product. (See also Side Effects section.) Follow your doctor's directions carefully.
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